Because DBM comes from human tissue, there is the risk of disease transmission and, of course, you must get the patient to sign an informed consent.

3.)  Infuse? 

STRENGTH:   Can grow bone at rates comparable to autograft. 

WEAKNESS:   Very expensive, limited FDA indications for use, significant side effect profile (antibody formation, ectopic bone formation, contraindicated in pregnant women, children under 18, and near tumors),  should only be used once in a patient’s lifetime.

4.)  β TCP? 

STRENGTH:   Excellent osteoconductive matrix, no risk of disease transmission, safe, proven efficacy, unlimited availability, multiple handling forms, FDA approved for a wide variety of indications, convenient application, cost effective.

WEAKNESS:  Not osteoinductive.

5.)  Platelet Jells?

STRENGTH:  Some efficacy in long bone use, available from patients own blood.

WEAKNESS:  Need to draw large quantities of blood, expensive centrifuge and disposables needed, preparation time, no osteoconductive scaffold, poor results in spine fusion, poor handling properties.

6.)  There is a unique new alternative:        Genex^®

·         Excellent osteoconductive matrix

·         No risk of disease transmission

·         Safe, proven efficacy

·         Unlimited availability

·         Multiple handling forms

·         FDA approved for a wide variety of indications,

·         Convenient application

·         Cost effective

Genex^® represents a new concept in synthetic bone graft materials.  It is totally resorbable, fully synthetic bone graft material which can be applied as an injectable paste to be contoured to the surgical site and which sets in-situ at body temperature.

Key Features and Benefits:

The key properties of Genex^® which distinguish the product from other bone void fillers include:

·  Zeta Potential Control (ZPC™)

·  Smart Pores

·  Load Bearing Characteristics

Genex^® has Zeta Potential Control (ZPC™), a property unique to bone void fillers which harnesses the key proteins involved in osteoblast differentiation.  To learn more about ZPC, click here.

Genex^® also contains "Smart Pores", a novel feature important for optimal bony incorporation and made possible through Genex^®'s proprietary matrix of porous β tri-calcium phosphate and implant grade calcium sulphate hemi-hydrate.  To learn more about Smart Pores, click here.

Genex^® has exceptional compressive strength characteristics to provide temporary fracture stabilization and it can be drilled to accommodate traditional augmentation hardware.

It resorbs predictably and consistently in sympathy with the body's ability to regenerate healthy new bone through the mechanism of creeping substitution.