Genex® is
a proprietary matrix of porous
β
tri-calcium phosphate and implant grade calcium sulphate hemi-hydrate.
Research has shown that these biomaterials resorb within the body in time frames
of several months and several weeks respectively and provide the chemical and
physical environment necessary for bone healing.
The successful healing of
bone defects is dependant upon a number of factors but includes the ability of
the healthy adjacent bone to regenerate and remodel before soft tissue can
invade the defect site. The presence of calcium sulphate within a bone
defect acts as a resorbable barrier, which prevents soft tissue infiltration,
while at the same time providing the soluble calcium ions essential for new bone
formation and mineralization.
The resorbing calcium
sulphate produces a developing macroporosity, to replace the initial
microporosity between the tri-calcium phosphate particles, which draws in cells
and nutrient fluids. This process of creeping substration exposes the
tri-calcium phosphate, which ten acts as a substrate for the cells involved in
new bone formation. The calcium phosphate resorbs more slowly and through
cell mediated process.
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